{"id":2282,"date":"2020-09-09T14:56:07","date_gmt":"2020-09-09T14:56:07","guid":{"rendered":"https:\/\/ayurvedanetworkbhu.com\/?p=2282"},"modified":"2022-03-12T09:42:49","modified_gmt":"2022-03-12T09:42:49","slug":"lecture-on-research-in-day-to-day-practice-by-dr-amit-nakanekar","status":"publish","type":"post","link":"https:\/\/ayurvedanetworkbhu.com\/?p=2282","title":{"rendered":"Module on &#8220;Research in Day-to-day Practice&#8221; by Dr. Amit Nakanekar"},"content":{"rendered":"<p><iframe loading=\"lazy\" src=\"https:\/\/www.youtube.com\/embed\/KvKt_XYfs9E\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<h1 style=\"text-align: center;\"><span style=\"color: #008000;\"><strong>Research in Day-to-day Practice<\/strong><\/span><\/h1>\n<p style=\"text-align: center;\"><strong><span style=\"color: #993366;\">Dr. Amit Nakanekar<\/span><br \/>\n<\/strong>MD (Ayu.), Ph.D., Assistant Professor,<br \/>\nDepartment of Kaychikitsa, Government Ayurveda College, Nagpur<\/p>\n<p style=\"text-align: justify;\">\u00a0Clinics or practice is routine part of our day-to-day life. Although many of us are interested in carrying out some kind of research. Still we may have many doubts, queries and problems regarding the research that can be formulated from day to day practice. So, here we are trying to cover the aspects of research those are concerned with day to day practice.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><span class=\"td_text_highlight_marker_yellow td_text_highlight_marker\" style=\"color: #800000;\"><strong>Image-1 Villagers are carrying the patient of a scorpion bite to PHC<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-3397 size-full\" src=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/1.png\" alt=\"\" width=\"939\" height=\"771\" srcset=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/1.png 939w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/1-300x246.png 300w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/1-768x631.png 768w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/1-160x131.png 160w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/1-696x571.png 696w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/1-512x420.png 512w\" sizes=\"auto, (max-width: 939px) 100vw, 939px\" \/><\/p>\n<p style=\"text-align: justify;\">\u00a0 In the given picture villagers are carrying the patient of a scorpion bite to a primary health care centre. Here patient is suffering from poisonous scorpion bite that can cause death of the patient. Another picture is of Dr.Himmatrao Bawaskar who has discovered the fact that scorpions bite can be fatal to cause a death.\u00a0 He observed this fact while working as Medical Officer in a PHC (primary health care centre) of Konkan area of Maharashtra. This area of Maharashtra is considered as a very remote place with lack of basic facilities like connectivity, transport and many more. In spite of facing lots of adverse conditions while working in a PHC, he found out the fact that a poisonous scorpion bite can kill a patient and treatment to reduce death rate. \u00a0So \u2018Necessity is Mother of Invention\u2019. You may go through some of these publications by Dr.Himmatrao Bawaskar.<\/p>\n<p style=\"text-align: center;\"><span class=\"td_text_highlight_marker_yellow td_text_highlight_marker\" style=\"color: #800000;\"><strong>Image -2 publications by Dr.Himmatrao Bawaskar<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-3398\" src=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/2.png\" alt=\"\" width=\"1064\" height=\"358\" srcset=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/2.png 1064w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/2-300x101.png 300w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/2-1024x345.png 1024w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/2-768x258.png 768w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/2-160x54.png 160w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/2-696x234.png 696w\" sizes=\"auto, (max-width: 1064px) 100vw, 1064px\" \/><\/p>\n<p style=\"text-align: justify;\">\u00a0 He has established a fact of pulmonary oedema after scorpion sting. A Lancet publication by him shows cardiac premonitory signs &amp; symptoms of red scorpion sting. Later he established the treatment in the form of tablet \u2018Prazocin\u2019 by observing its role in prevention of pulmonary oedema and decrease in death rates. It is praiseworthy to note that all these publications came from him, while he was working in a remote area of Maharashtra. [1]<\/p>\n<p style=\"text-align: justify;\">\u00a0\u00a0 Another remote area in Maharashtra is Gadchiroli. It is a very remote, densely forested, underdeveloped area, and mostly affected by terrorist\u2019s activities. Higher incidence of neonatal mortality was one of the problem of community leaving in this area. There is a couple named Dr. Abhay Bang &amp; Dr. Rani Bang who found out some innovative and simple thought called \u2018Kangaroo\u2019 method. In spite of having a lot of poverty &amp; lack of the instruments and advanced gadgets, out of reach to new world; neonates and children of residential community can be raised safely by adopting this simple method. This \u2018Kangaroo\u2019 method established by them later on accepted by WHO. This couple published more than 500 research articles while just sitting in Gadchiroli area of Maharashtra. WHO has released a statement for adoption of \u2018Kangaroo\u2019 method to reduce neonatal mortality. Even this couple contributed a lot in other fields related to neonatal mortality and child hood pneumonia. So it is meant that, it is false to suggest that medical breakthroughs come only through government research. [2]<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><span class=\"td_text_highlight_marker_yellow td_text_highlight_marker\" style=\"color: #800000;\"><strong>Image 2. publication by Dr. Abhay Bang and Dr.Rani Bang:<\/strong><\/span><\/p>\n<h3 style=\"clear: both; text-align: justify;\"><span style=\"background-color: #000000;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-3399\" src=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/3.png\" alt=\"\" width=\"1103\" height=\"745\" srcset=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/3.png 1103w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/3-300x203.png 300w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/3-1024x692.png 1024w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/3-768x519.png 768w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/3-160x108.png 160w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/3-696x470.png 696w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/3-1068x721.png 1068w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/3-622x420.png 622w\" sizes=\"auto, (max-width: 1103px) 100vw, 1103px\" \/><\/span><\/h3>\n<h3 style=\"text-align: justify;\"><span style=\"color: #008080;\"><strong>What is Relationship between Research and practice?<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\">Good research is necessary to improve our practice. While good practice &amp; good observation in our practice can lead to some good research which in turn is responsible for improvement in practice. A good practice and good research both are interdependent. It means that there is impact of good research on a practices i.e. good research can bring-out some new medicine, new technology, new adaptation, new method that will help to improve practice. Good practice along with good observations also can generate very good research question. Therefore we have to keep balance between good research and good practice .So that we will continue to do both good research as well as good practice.<\/p>\n<p style=\"text-align: justify;\">\u00a0In this lecture we will learn about \u2018Reverse Pharmacology\u2019, Case Studies and Case Reports, unusual findings, various Clinical Studies and \u2018Evidence Based medicine\u2019.<\/p>\n<h3 style=\"text-align: justify;\"><span style=\"color: #008080;\"><strong>How research can be done in practice?<\/strong><\/span><\/h3>\n<h4 style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Reverse Pharmacology:<\/strong><\/span><\/h4>\n<p style=\"text-align: justify;\">\u00a0\u00a0\u00a0\u00a0 \u00a0Dr.Ashok Vaidya has done some remarkable things. He is a pioneer in establishing fast track of reverse pharmacology for research in Ayurveda. In a conventional pharmacology, the way for development of drug is from benches to beds. The sequential pattern includes establishment of Molecule <span style=\"color: #0000ff;\"><strong>\u2192 <\/strong><\/span>Pre-Clinical Studies <strong><span style=\"color: #0000ff;\">\u2192<\/span><\/strong> Animal Studies <strong><span style=\"color: #0000ff;\">\u2192 <\/span><\/strong>Market.<\/p>\n<p style=\"text-align: justify;\">\u00a0 It is a quiet expensive and time consuming. While in case of Ayurveda, we are already using the medicine in our clinical practice, therefore by following reverse order i.e. from clinics to benches we can find out the things\/fact that were resulted in the form of efficacy. Dr.Ashok Vaidya sir has been established this approach known as \u2018Reverse Pharmacology\u2019. [3]<\/p>\n<p style=\"text-align: center;\"><span class=\"td_text_highlight_marker_yellow td_text_highlight_marker\" style=\"color: #993366;\"><strong>Image 3.\u00a0\u00a0 The format for clinics to laboratory<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-3400\" src=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/4.png\" alt=\"\" width=\"1193\" height=\"688\" srcset=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/4.png 1193w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/4-300x173.png 300w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/4-1024x591.png 1024w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/4-768x443.png 768w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/4-160x92.png 160w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/4-696x401.png 696w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/4-1068x616.png 1068w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/4-728x420.png 728w\" sizes=\"auto, (max-width: 1193px) 100vw, 1193px\" \/><\/p>\n<p style=\"text-align: justify;\">So this is an exact mechanism from \u2018Clinics to Laboratory\u2019. In case of Ayurveda research we can follow similar approach i.e. from \u2018Clinics to Laboratory\u2019. Because in routine Ayurvedic practice many of formulations are already in use.<\/p>\n<h3 style=\"text-align: justify;\"><span style=\"color: #008080;\"><strong>Various types of studies \u2013<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\">What are the different type of clinical studies that we can do in our day to day practice &amp; our day to day clinical set up?<\/p>\n<ol>\n<li style=\"text-align: justify;\"><strong><span style=\"color: #993366;\">Descriptive study: \u2013<\/span><\/strong> This is a type of study where clinician can describe a kind of patient, observations or experiences without comparing to any group. The researcher, clinicians interact with the participant through survey or Interviews to collect necessary data or information.<\/li>\n<li style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Analytical study &#8211;<\/strong> <\/span>This type of study needs comparison group e.g. comparison between normal and diseased individuals, comparison between alcohol addicted and non-addicted individuals.<\/li>\n<\/ol>\n<h4 style=\"text-align: justify;\"><span style=\"color: #008080;\"><strong>Descriptive study has two types &#8211;<\/strong><\/span><\/h4>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>A)\u00a0\u00a0\u00a0 Personal level individuals study \u00a0:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>1.\u00a0\u00a0\u00a0\u00a0 Case reports:<\/strong><\/span> It includes individual case report consisting of some new or interesting findings and treatment. Though case report is first level of evidence, it may help while treating the patients. Similarly it can provide some important leads to the science to manage tricky situations or it can provide some kind of innovation.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>2.\u00a0\u00a0\u00a0\u00a0 Case series:<\/strong> <\/span>Reporting of case series of non-specific pneumonia has been brought attention on the emergence of the new disease. Later on this disease term as COVID-19 by WHO. This case series is responsible to bring some important breakthroughs to our day to day practice. The emergence of COVID-19 has be identified by Case series itself.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>3.\u00a0\u00a0\u00a0\u00a0 Cross sectional study:<\/strong> <\/span>\u00a0It is single examination study. Identifying risk factor is the first objective of this study. It is also very useful to find the prevalence rate of various diseases. [5]<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>4.\u00a0\u00a0\u00a0\u00a0 Surveillance study<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><strong><span style=\"color: #993366;\">B) \u00a0Aggregate level population type study:\u00a0 It includes ecological correlation <span style=\"color: #000000;\">study:<\/span><\/span><\/strong><\/p>\n<p style=\"text-align: center;\"><span class=\"td_text_highlight_marker_yellow td_text_highlight_marker\" style=\"color: #993366;\"><strong>Algorithm for classification of clinical research? \u2013<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-3401\" src=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/5.png\" alt=\"\" width=\"634\" height=\"539\" srcset=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/5.png 355w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/5-300x255.png 300w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/5-160x136.png 160w\" sizes=\"auto, (max-width: 634px) 100vw, 634px\" \/><\/p>\n<p style=\"text-align: justify;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-3402\" src=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/6.png\" alt=\"\" width=\"674\" height=\"413\" srcset=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/6.png 532w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/6-300x184.png 300w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/6-160x98.png 160w\" sizes=\"auto, (max-width: 674px) 100vw, 674px\" \/><\/p>\n<p style=\"text-align: justify;\">\u00a0\u00a0Did investigator has any exposure? If it is yes-then experimental trial and if it is no- then observational study.<\/p>\n<p style=\"text-align: justify;\">In observational study, investigator do not implement any kind of intervention however he\/she will observe the group in curious way or detail way. If an observational study has comparator group then it will be analytical study.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>\u00a0Example \u2013<\/strong><\/span> Observation among the groups of alcoholic and non-alcoholic individuals.\u00a0 If we want to study whether alcohol can cause cirrhosis of liver? \u00a0Individuals going to be observed can be allocated like,<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Group A.<\/strong><\/span> Individuals consuming alcohol and having cirrhosis.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Group B<\/strong>.<\/span> Individuals not consuming alcohol but having cirrhosis of liver.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Group C:<\/strong> <\/span>Individuals consuming alcohol but not having cirrhosis of liver.<\/p>\n<p style=\"text-align: justify;\">\u00a0By observing these three groups we can perform an \u2018Analytical study\u2019.\u00a0 When there is no comparison group then it will be \u2018Descriptive study\u2019. If there is a random allocation for experimental studies then it will become a \u2018Randomized Clinical Trial and no random allocation then it will become a \u2018Non-randomized clinical trial\u2019.<\/p>\n<p style=\"text-align: justify;\">There is time direction for \u2018Analytical studies\u2019. The three types are<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>1) Cohort study<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>2) Case Control study<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>3) Cross sectional study<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Case control study:<\/strong><\/span> In this type of study, method used is from outcome to exposure e.g group of individuals having disease with or without prior exposure to particular substance \/ factor will be considered as \u2018Case\u2019. While very similar individuals having no disease with or without prior exposure to particular substance \/factor will be considered as \u2018Control\u2019.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Cohort study:<\/strong> <\/span>In case of cohort study which usually follow a participants selected on the basis of exposure\u00a0\u00a0\u00a0\u00a0 e.g. average \u00a0\u00a0duration for onset of liver cirrhosis can be predicted by observing the persons who are taking alcohol very often.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Cross section study:<\/strong><\/span> Exposure and outcome is measured at same time.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Case report and Case series<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\">Case report includes single case. While case series includes more than one patient that has been reported by researcher. Case report is simplest study design and very weak evidence, yet it gives unusual thought provoking phenomena. Investigators are often practicing clinicians. Therefore it is very important to record a case in a good way or to report a case series as far as practicing clinicians are concerned.\u00a0 Case reports &amp; case series has ability to generate a research question and also gives answer for that research question. If you don&#8217;t ask research question you will never get answer.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Case report- CARE TEMPLATE<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\">\u00a0 Case reports has to be published after following specific guideline called as \u2018CARE\u2019 guideline. CARE guideline are initially published in 2013 in Journal of epidemiology under leadership of Dr David Riley. This guidelines gives a specific template and sequence for publication of case report.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>General considerations:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\">Ensure that all patient data has been DE identified and obtained the necessary approval, consent or consent from of hospital. Mention that you don&#8217;t have any competing or conflict of interests.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Title \u2013 <\/strong><\/span>It should include word \u201cCase Report.\u2019\u2019<\/p>\n<p style=\"text-align: justify;\">The title should be sufficient enough to describe greatest interest of the author. This could be way to present the diagnosis, test results, the interventions or the outcome.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Abstract<\/strong> \u2013<\/span> It should be written in about 200 words. Summarize the following information if relevant<\/p>\n<p style=\"text-align: justify;\">1) Rationale for this case report<br \/>\n2) Presenting concerns of the patient (such as chief complaints or symptoms, diagnosis)<br \/>\n3) Interventions (such as diagnostic, preventive, prognostic, therapeutic exchange)<br \/>\n4) Outcomes<br \/>\n5) Main lessons to be learn from this case report.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Key words &#8211;<\/strong><\/span> Provide 2 to 5 key words that will help readers to search and find this case report.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Introduction &#8211; <\/strong><\/span>Briefly summarize the background and context of this case report<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Presenting concerns &#8211;<\/strong><\/span> Describe the patient characteristics (such as the relevant demographics &#8211; age, gender ethnicity, occupation) and their presenting concerns with relevant details of related past interventions<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Clinical findings &#8211;<\/strong><\/span> Describe the<\/p>\n<p style=\"text-align: justify;\">(1) Medical, family &amp; psychological history including lifestyle &amp; genetic information<\/p>\n<p style=\"text-align: justify;\">(2) Other pertinent co-morbidities interventions (other therapies including self-care)<\/p>\n<p style=\"text-align: justify;\">(3) The physical examination (PE) focused on the important findings including results from testing<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Timeline-<\/strong><\/span> create a timeline that includes specific date and times in a table, figure, or graphic. Visit www.care statement org \/ case report example, for one example of a \u2018Case report\u2019 timeline.<\/p>\n<h3 style=\"text-align: justify;\"><span style=\"color: #008080;\"><strong>Diagnostic Focus &amp; Assessment- provide an assessment of the<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\">1) Diagnostic methods (including laboratory testing, imaging results, questionnaires, referral diagnostic information)<\/p>\n<p style=\"text-align: justify;\">2) Diagnostic challenges (such as limited ability to complete an evaluation, patient availability, cultural)<\/p>\n<p style=\"text-align: justify;\">3) Diagnostic reasoning including other diagnosis considered<\/p>\n<p style=\"text-align: justify;\">4) Prognostic characteristics (such as staging in oncology)<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Therapeutic focus &amp; Assessment &#8211;<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\">\u00a01) Types of Intervention (such as pharmacologic, surgical, preventive, lifestyle, self-care)<\/p>\n<p style=\"text-align: justify;\">\u00a02) Administration &amp; intensity of the intervention (including dosage, strength, duration, frequency.)<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Follow up &amp; Outcomes &#8211; describe the clinical course of this case including all follow up visit as well as<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\">1) Intervention modification, interruption or discontinuation and the reasons<\/p>\n<p style=\"text-align: justify;\">2) Adherence to the intervention and how this was assessed.<\/p>\n<p style=\"text-align: justify;\">3) Adverse effects or unanticipated events<\/p>\n<p style=\"text-align: justify;\"><strong>Also describe. &#8211;<\/strong><\/p>\n<p style=\"text-align: justify;\">1) Patient reported outcomes<\/p>\n<p style=\"text-align: justify;\">2) Clinician assessed and reported outcomes<\/p>\n<p style=\"text-align: justify;\">\u00a03) Important positive &amp; Negative, test results.<\/p>\n<h3 style=\"text-align: justify;\"><strong><span style=\"color: #008080;\">Discussion &#8211;<\/span><\/strong><\/h3>\n<p style=\"text-align: justify;\">\u00a0 Describe the strength and limitations of this case report including case management, the scientific and medical literature related to this case report. Discuss the rationale for your conclusion potential causation &amp; the ways this case might be generalized to a larger population. Finally main findings of this case report and \u2018take away\u2019 messages should be written.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Patient Perspective<\/strong> \u2013<\/span>Wherever appropriate the patient should share their experience of their care in a narrative published within this case report or accompanying this case report.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Informed consent &#8211;<\/strong><\/span> Ensure that the patient provided there Informed consent for the publication of this case report.<\/p>\n<h3 style=\"text-align: justify;\"><span style=\"color: #008080;\"><strong>Examples of published case study in PubMed-<\/strong><\/span><\/h3>\n<h6 style=\"text-align: justify;\">1) Guillian Barre syndrome associated with COVID -19 infection &#8211; a case report. <span style=\"color: #3366ff;\">[4]<\/span><\/h6>\n<p style=\"text-align: justify;\">2) An Ayurvedic approach in the management of Guillian Barre syndrome &#8211; A case study [5]<\/p>\n<p style=\"text-align: justify;\">3) Analysis of Virechana karma with Danti avaleha A retrospective study &#8211; case series published in Journal of Ayurveda &amp; Integrity medicine.[6]<\/p>\n<p style=\"text-align: justify;\">This type of case series can be published by any Vaidya (Ayurveda clinician) or clinicians from Kayachikitsa branch those are dealing with such type of cases in their day to day clinical practice. This type of case series can give boost to improve the clinical practice.<\/p>\n<h3 style=\"text-align: justify;\"><span style=\"color: #008080;\"><strong>Guidelines of various types of studies<\/strong><\/span><\/h3>\n<ul style=\"text-align: justify;\">\n<li style=\"text-align: justify;\">Search a website Equator network.org, to find guidelines for various types of studies.<\/li>\n<li style=\"text-align: justify;\">CONSORT Guideline \u2013 RCT (Randomised controlled trial)<\/li>\n<li style=\"text-align: justify;\">STROBE Guideline &#8211; observational study<\/li>\n<li style=\"text-align: justify;\">PRISMA Guidelines- systematic review<\/li>\n<li style=\"text-align: justify;\">SPIRIT Guidelines -study protocol<\/li>\n<li style=\"text-align: justify;\">STARD Guidelines- diagnostic\/ prognostic studies<\/li>\n<li style=\"text-align: justify;\">CARE Guidelines-case report<\/li>\n<li style=\"text-align: justify;\">AGREE Guideline &#8211; clinical practice guideline<\/li>\n<li style=\"text-align: justify;\">SRQR Guidelines- qualitative research<\/li>\n<li style=\"text-align: justify;\">ARRIVE Guideline- Animal pre- clinical studies.<\/li>\n<li style=\"text-align: justify;\">SQUIRE Guidelines- quality improvement studies<\/li>\n<li style=\"text-align: justify;\">CHEERS Guideline -economics evaluation<\/li>\n<\/ul>\n<p style=\"text-align: justify;\">CONSORT guide line should be followed for performing various clinical trials. Image given below depicts CONSORT flow diagram. While performing clinical trial, it is essential to solve CONSORT statements (25 item checklist) and also mention flow diagram. Visit to CONSORT Guideline, the CONSORT statement website &amp; go through the details of how to follow. [7]<\/p>\n<p style=\"text-align: justify;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-3403\" src=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/7.png\" alt=\"\" width=\"4501\" height=\"4529\" srcset=\"https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/7.png 4501w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/7-298x300.png 298w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/7-1018x1024.png 1018w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/7-150x150.png 150w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/7-768x773.png 768w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/7-160x160.png 160w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/7-1527x1536.png 1527w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/7-2035x2048.png 2035w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/7-696x700.png 696w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/7-1068x1075.png 1068w, https:\/\/ayurvedanetworkbhu.com\/wp-content\/uploads\/2022\/03\/7-417x420.png 417w\" sizes=\"auto, (max-width: 4501px) 100vw, 4501px\" \/><\/p>\n<h3 style=\"text-align: justify;\"><span style=\"color: #008080;\"><strong>Registration of Clinical Trial is mandatory &#8211;<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\">\u00a0\u00a0\u00a0\u00a0 Before performing clinical trial, its registration is mandatory. Before recruiting any subject of your clinical studies, you have to register for CTRI. (Clinical Trial Registry India)<\/p>\n<h3 style=\"text-align: justify;\"><span style=\"color: #008080;\"><strong>Unusual clinical findings-<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\">Some unusual clinical findings has to be reported. Here two examples of treated case from our hospital has been displayed. First example is pseudohermaphroditism. In this patient\u2019s clitoris is looking like a glans penis, eventually it was diagnosed as late onset adrenal hyperplasia. We treated this case with Ayurvedic management and presently patient is living very nice life. Another example is of purple colour urination. Snaps can be used for reporting unusual findings.<\/p>\n<h3 style=\"text-align: justify;\"><span style=\"color: #008080;\"><strong>Standardization clinical procedures-<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\">One of the area providing research opportunity to Ayurveda clinicians could be \u2018Standardization of clinical procedures\u2019. Automated instruments can be developed for the purpose of standardization of clinical procedures. Development of standard instrument and outcomes derived through it has to be published.<\/p>\n<p style=\"text-align: justify;\">\u00a0E.g. Auto enema apparatus, Naditarangini instrument (\u0928\u093e\u0921\u0940 \u0924\u0930\u0902\u0917\u093f\u0923\u0940). Data generated through instruments can be utilized for publication purpose.<\/p>\n<h3 style=\"text-align: justify;\"><span style=\"color: #008080;\"><strong>Evidence Based Medicine:<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\">Impact of good research on practice can be learned through EBM.(Evidence Based Medicine) The physician who knows EBM better can do the practice in much better way. \u00a0Guyatt firstly mentioned EBM in 1991. It is about integrating individual clinical expertise with best available clinical evidence derived from systemic research. It should be conscience, explicit and judicious use of current best evidence in making decisions about individual patient.<\/p>\n<p style=\"text-align: justify;\">e.g .How can a patient of particular disease will get the best treatment plan based on recent research? You can do PubMed search based on evidence available and after matching those evidences with actual patient data, you can select the best treatment to be offered to the particular patient in that particular scenario. Such type of integration is called as evidence based medicine. When you are educated you will believe on only half of what you hear and read. But when you are knowledgeable and intelligent enough, you will know which half to believe &amp; which half not to believe.<\/p>\n<h3 style=\"text-align: justify;\"><span style=\"color: #008080;\"><strong>\u00a0Hierarchy of Evidence Based Medicine<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\">\u00a0Where we can find components of evidence based medicine?<\/p>\n<p style=\"text-align: justify;\">1) Cochrane Data Base<\/p>\n<p style=\"text-align: justify;\">2) Other Meta-Analysis.<\/p>\n<p style=\"text-align: justify;\">3) Randomized control Blinded trials<\/p>\n<p style=\"text-align: justify;\">4) Randomized control unblinded Trial<\/p>\n<p style=\"text-align: justify;\">5) Randomized uncontrolled Trial<\/p>\n<p style=\"text-align: justify;\">6) Non Randomized controlled trial<\/p>\n<p style=\"text-align: justify;\">7) Publications on <a href=\"http:\/\/www.rhlibrary.com\">www.rhlibrary.com\u00a0<\/a><\/p>\n<p style=\"text-align: justify;\">8) Observational studies.<\/p>\n<p style=\"text-align: justify;\">9) Review Articles.<\/p>\n<p style=\"text-align: justify;\">10) Cross sectional study<\/p>\n<p style=\"text-align: justify;\">11) Editorials<\/p>\n<p style=\"text-align: justify;\">12) Clinical practice guidelines<\/p>\n<p style=\"text-align: justify;\">13) Electronic database like DHARA, Pubmed, Ayush portal<\/p>\n<p style=\"text-align: justify;\">14) Clinical trial registries<\/p>\n<p style=\"text-align: justify;\">15) Monographs and textbook<\/p>\n<p style=\"text-align: justify;\">16) Internet sources<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Level of Evidence:<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\">Level A- Good scientific evidence. You must discuss this service\/investigation \/treatment with eligible patients. Risk to benefit is more.<\/p>\n<p style=\"text-align: justify;\">Level B- Fair scientific evidence<\/p>\n<p style=\"text-align: justify;\">Level C- Fair scientific evidence but balance between risk to benefit is narrow<\/p>\n<p style=\"text-align: justify;\">Level D- Fair Evidence suggests that risk &gt; benefits<\/p>\n<p style=\"text-align: justify;\">Level E- Scientific evidence lacking or Poor. Clinicians should help patient to understand uncertainty.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Limitations of Evidence Based Medicine-<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\">1) Characteristics of patients to RCT may be different than the patient which physician is confronted e.g., &#8211; Race, Genetics, Culture, Environment.<\/p>\n<p style=\"text-align: justify;\">2) Clinicians may have specific query regarding some aspects which could be too narrow to be assessable by studies.<\/p>\n<p style=\"text-align: justify;\">3) Besides there are no RCT to support or to reject half of clinicians do in patient care and take decisions.<\/p>\n<p style=\"text-align: justify;\">4) Patient may choose less effective therapy.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>Obstacles in Evidence Based Medicine<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\">1) Ignorant, Reluctant, Medical Representative Dependent clinicians &#8211; do not spend time in reading actual evidence.<\/p>\n<p style=\"text-align: justify;\">2) Pharma companies<\/p>\n<p style=\"text-align: justify;\">3) Scarcity of evidences &#8211; maximum up to 35% medical care is based on RCT<\/p>\n<p style=\"text-align: justify;\">4) Patients ignorant and prejudices mind set.<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #993366;\"><strong>How to overcome the limitations?<\/strong><\/span><\/p>\n<p style=\"text-align: justify;\">1) Try to read evidences and stay updated.<\/p>\n<p style=\"text-align: justify;\">2) Follow \u2018Good Clinical Practice\u2019 guidelines.<\/p>\n<p style=\"text-align: justify;\">3) Try to analyse medical representative\u2019s report in scientific way.<\/p>\n<p style=\"text-align: justify;\">4). Don\u2019t forget, all of us who treat patients every day will be become patient someday&#8230;<\/p>\n<p style=\"text-align: justify;\"><strong>WHY &#8211;<\/strong> Research is to see what everybody else has seen, and to think what nobody else has thought. (Albert &#8211; Szent-Gyorgyi)<\/p>\n<table style=\"height: 2851px;\" width=\"696\">\n<tbody>\n<tr>\n<td width=\"717\"><span class=\"td_text_highlight_marker_blue td_text_highlight_marker td_text_highlight_marker_green\" style=\"color: #ffffff;\"><strong><span style=\"color: #000000;\">Multiple choice question<\/span>\u00a0<\/strong><\/span><\/p>\n<p><strong>1)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Who played pivotal role in establishing fast track of reverse pharmacology?<\/strong><\/p>\n<p>(a)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Dr. Himmat Rao Bawaskar<\/p>\n<p>(b)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Dr. Ashok Vaidya<\/p>\n<p>(c)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Dr. Abhay Bang<\/p>\n<p>(d)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Dr. Rani Bang<\/p>\n<p><strong>2)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Some normal individuals addicted to something and some are not addicted to that, if we consider occurrence of particular disease with that addiction What type of observational study is this?<\/strong><\/p>\n<p>(a)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Descriptive study<\/p>\n<p>(b)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Analytical study<\/p>\n<p>(c)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Surveillance study<\/p>\n<p>(d)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 None of the above<\/p>\n<p><strong>3)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Which study is useful to find prevalence rate of various diseases?<\/strong><\/p>\n<p>(a)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Cohort<\/p>\n<p>(b)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Case series<\/p>\n<p>(c)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Cross sectional<\/p>\n<p>(d)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Ecological correlation<\/p>\n<p><strong>4)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 In which of following study participants are selected on the basis of exposure?<\/strong><\/p>\n<p>(a)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Cohort study<\/p>\n<p>(b)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Case control study<\/p>\n<p>(c)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Cross sectional study<\/p>\n<p>(d)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Case report<\/p>\n<p><strong>5)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Which of following guidelines has to be followed for carrying out qualitative research?<\/strong><\/p>\n<p>(a)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 STROBE<\/p>\n<p>(b)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 SQUIRE<\/p>\n<p>(c)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 STARD<\/p>\n<p>(d)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 SRQR<\/p>\n<p><strong>6)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 In which level of Evidence, scientific evidence is lacking or poor, therefore clinicians should help patient to understanding uncertainty.<\/strong><\/p>\n<p>(a)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Level E<\/p>\n<p>(b)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Level D<\/p>\n<p>(c)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Level C<\/p>\n<p>(d)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Level B<\/p>\n<p><strong>7)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Level B is \u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026.<\/strong><\/p>\n<p>(a)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Fair Evidence suggests that risk &gt; benefits<\/p>\n<p>(b)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Fair scientific evidence but balance between risk to benefit is narrow<\/p>\n<p>(c)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Fair scientific evidence<\/p>\n<p>(d)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Good scientific Evidence should discuss service with Eligible patients.<\/p>\n<p><strong>8)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Which of the following is limitations of EBM?<\/strong><\/p>\n<p>(a)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Ignorant, reluctant, Medical Representative dependent clinicians<\/p>\n<p>(b)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Characteristics of patients e.g., &#8211; Race, Genetics, Culture, Environment.<\/p>\n<p>(c)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Pharma companies<\/p>\n<p>(d)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 patients ignorant and prejudices mind set.<\/p>\n<p><strong>9)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Who published Care Guidelines?<\/strong><\/p>\n<p>(a)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 David Riley<\/p>\n<p>(b)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 David Shaw<\/p>\n<p>(c)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 David Baltimore<\/p>\n<p>(d)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 David Deming<\/p>\n<p><strong>10)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Which of the following is impact of Good Clinical research on practice?<\/strong><\/p>\n<p>(a)\u00a0\u00a0\u00a0 some new medicines,<\/p>\n<p>(b)\u00a0\u00a0 some new technology,<\/p>\n<p>(c)\u00a0\u00a0\u00a0 some newer adaptation<\/p>\n<p>(d)\u00a0\u00a0 all of above<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"height: 657px;\" width=\"525\">\n<tbody>\n<tr>\n<td width=\"98\"><strong>Question no<\/strong><\/td>\n<td width=\"98\"><strong>Answer<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"98\">1<\/td>\n<td width=\"98\">b<\/td>\n<\/tr>\n<tr>\n<td width=\"98\">2<\/td>\n<td width=\"98\">b<\/td>\n<\/tr>\n<tr>\n<td width=\"98\">3<\/td>\n<td width=\"98\">c<\/td>\n<\/tr>\n<tr>\n<td width=\"98\">4<\/td>\n<td width=\"98\">a<\/td>\n<\/tr>\n<tr>\n<td width=\"98\">5<\/td>\n<td width=\"98\">d<\/td>\n<\/tr>\n<tr>\n<td width=\"98\">6<\/td>\n<td width=\"98\">a<\/td>\n<\/tr>\n<tr>\n<td width=\"98\">7<\/td>\n<td width=\"98\">c<\/td>\n<\/tr>\n<tr>\n<td width=\"98\">8<\/td>\n<td width=\"98\">b<\/td>\n<\/tr>\n<tr>\n<td width=\"98\">9<\/td>\n<td width=\"98\">a<\/td>\n<\/tr>\n<tr>\n<td width=\"98\">10<\/td>\n<td width=\"98\">d<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\"><strong>References-<\/strong><\/p>\n<p style=\"text-align: justify;\">1.\u00a0\u00a0\u00a0\u00a0 Kale A. A. (2012). A crusade against scorpion sting: life and works of dr. Himmatrao bawaskar.\u00a0Journal of family medicine and primary care,\u00a01(1), 52\u201355. https:\/\/doi.org\/10.4103\/2249-4863.94453<\/p>\n<p style=\"text-align: justify;\">2.\u00a0\u00a0\u00a0\u00a0 Bang A. T. (1991). Pneumonia and Child Mortality in India.\u00a0The National medical journal of India,\u00a04(4), 157\u2013158.<\/p>\n<p style=\"text-align: justify;\">3.\u00a0\u00a0\u00a0\u00a0 Patwardhan, B., &amp; Vaidya, A. D. (2010). Natural products drug discovery: accelerating the clinical candidate development using reverse pharmacology approaches.\u00a0Indian journal of experimental biology,\u00a048(3), 220\u2013227.<\/p>\n<p style=\"text-align: justify;\">4.\u00a0\u00a0\u00a0\u00a0 Randhawa, J., Randhawa, H. S., &amp; Toor, P. (2021). Pharyngeal-Cervical-Brachial Variant of Guillain-Barr\u00e9 Syndrome in a Patient of COVID-19 Infection.\u00a0Cureus,\u00a013(9), e17945. https:\/\/doi.org\/10.7759\/cureus.17945<\/p>\n<p style=\"text-align: justify;\">5.\u00a0\u00a0\u00a0\u00a0 Nakanekar, A., Bhople, S., Gulhane, H., Rathod, S., Gulhane, J., &amp; Bonde, P. (2015). An ayurvedic approach in the management of Guillain-Barre syndrome: A case study.\u00a0Ancient science of life,\u00a035(1), 52\u201357. https:\/\/doi.org\/10.4103\/0257-7941.164540<\/p>\n<p style=\"text-align: justify;\">6.\u00a0\u00a0\u00a0\u00a0 Chaganti, S., &amp; Prasad, B. S. (2015). Analysis of Virechana karma with Danti avaleha: A retrospective study.\u00a0Journal of Ayurveda and integrative medicine,\u00a06(4), 300\u2013304. https:\/\/doi.org\/10.4103\/0975-9476.172420<\/p>\n<p style=\"text-align: justify;\">7.\u00a0\u00a0\u00a0\u00a0 http:\/\/www.consort-statement.org\/consort-statement\/flow-diagram accessed on 20 October 2020<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; Research in Day-to-day Practice Dr. Amit Nakanekar MD (Ayu.), Ph.D., Assistant Professor, Department of Kaychikitsa, Government Ayurveda College, Nagpur \u00a0Clinics or practice is routine part of our day-to-day life. Although many of us are interested in carrying out some kind of research. Still we may have many doubts, queries and problems regarding the research [&hellip;]<\/p>\n","protected":false},"author":20,"featured_media":3236,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"video","meta":{"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[116,127,34,54],"tags":[],"class_list":["post-2282","post","type-post","status-publish","format-video","has-post-thumbnail","hentry","category-complete-module","category-dr-amit-nakanekar","category-kaya-chikitsa","category-videos","post_format-post-format-video"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.0.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"Research in Day-to-day Practice Dr. Amit Nakanekar MD (Ayu.), Ph.D., Assistant Professor, Department of Kaychikitsa, Government Ayurveda College, Nagpur Clinics or practice is routine part of our day-to-day life. 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